Kent D. Chapman

BDI Associate Director / Regents Professor
Biological Sciences

Chapman lab

Kent Chapman completed a B.A. degree in biology in 1986 from Lycoming College in Williamsport, PA. He then traveled Tempe, AZ, where he earned a Ph.D. degree in botany (plant cell biology) at Arizona State University under the supervision of Richard N. Trelease for studies on peroxisome membrane lipids.  After completing his doctoral degree, Chapman was awarded a 2-year NSF postdoctoral fellowship to study plant biochemistry with Thomas S. Moore, Jr., at Louisiana State University in Baton Rouge, LA.  In 1993, he accepted a position as a tenure-track, Assistant Professor of Biochemistry at the University of North Texas (UNT) in Denton. During the last 20+ years, Chapman has developed an internationally-recognized research program in plant biochemistry and cell biology, specifically in the area of plant lipid metabolism.  The Chapman lab has contributed more than 100 publications to the primary plant biology and biochemistry literature, and new ideas about the evolutionary conservation of lipid metabolism and function in eukaryotes have emerged from these efforts.  With John Ohlrogge (Michigan State), Chapman proposed and chaired the inaugural Gordon Research Conference on Plant Lipids: Structure, Metabolism and Function in 2009 in Galveston TX.  Chapman is co-inventor on six patents (issued or pending), and in 2010 was recognized with an award for Outstanding Achievement in Intellectual Property at UNT.  Chapman received the first ever Research Leadership Award at UNT for National and International Scientific Achievement in Research, and in 2010 was appointed Regents Professor of Biochemistry.  In January, 2014, he took leave from UNT for eighteen months to serve as Program Director at the US National Science Foundation’s Division of Integrative Organismal Systems.  Chapman currently serves as Associate Director of the BioDiscovery Institute. He is Executive Editor for the journal, Progress in Lipid Research, and has a guest editor appointment with The Plant Cell.

Research Interests: 
  • Lipid signaling in plants.
  • Compartmentalization of neutral lipids in plant cells.
  • Plant lipids for human health and industrial applications.
  • Lipidomics in tissues and organelles.
  • United States Department of Energy, Office of Science, Basic Energy Sciences, Physical Biosciences program. Elucidating the Cellular Machinery for Storage Lipids in Plants. (Kent Chapman, PI, Robert Mullen, Co-PI, John Dyer, Co-PI). $650,000.00. 9/1/2016 – 8/31/2019.
  • United States Department of Energy, Office of Science, Basic Energy Sciences, Physical Biosciences program. N-Acylethanolamine (NAE) metabolism and the acquisition of photoautotrophy during seedling establishment. (PI) $360,000.00. 9/1/2014–8/31/2017.
  • United States Department of Agriculture- Agricultural Research Service- Cooperative Research Award. Characterizing Neutral Lipid Compartmentation and its Relationship to Plant Stress Response. (PI Kent Chapman). $38,219.00. 1/1/16–5/31/17.
  • Cotton Incorporated. Genetic Manipulation of Cottonseed Protein Reserves. (PI) $650,000.00 since 2008 ($55,000.00 awarded in 2016). 1/1/08-12/31/16.
Publications: 

Full List:  Google Scholar

Sofia K Marmon, Drew Sturtevant, Cornelia Herrfurth, Kent D. Chapman, Sten Stymne, and Ivo Feussner Two acyltransferases contribute differently to linolenic acid levels in seed oil Plant Physiology April 2017 vol. 173 no. 4 2081-2095. http:/ / dx. doi. org/ 10. 1104/ pp. 16. 01865

Keereetaweep, J., Blancaflor, E.B., Hornung, E., Feussner, I. and Chapman, K.D. (2015). Lipoxygenase derived 9-hydro(pero)xides of linoleoylethanolamide interact with ABA signaling to arrest root development during Arabidopsis seedling establishment. Plant Journal Apr;82(2):315-27. doi: 10.1111/tpj.12821.

Phelps, M.S., Sturtevant, D., Chapman, K.D. and Verbeck, G.F. (2015). Nanomanipulation-coupled matrix-assisted laser desorption/ ionization-direct organelle mass spectrometry: A technique for the detailed analysis of single organelles. Journal of the American Society of Mass Spectrometry (JASMS) 27(2):187-93. PMID: 26238327. (cover of issue)

Cai, Y., Goodman, J.M., Pyc, M., Mullen, R.T., Dyer, J.M. and Chapman, K.D. (2015). Arabidopsis SEIPIN proteins modulate triacylglycerol accumulation and influence lipid droplet proliferation. Plant Cell 27(9):2616-36. pii: tpc.15.00588.

Keereetaweep, J., Blancaflor, E.B., Hornung, E., Feussner, I. and Chapman, K.D. (2013). Ethanolamide oxylipins of linolenic acid can negatively regulate Arabidopsis seedling development. Plant Cell, 25(10):3824-40. (featured in-brief article in same issue)

Horn, P.J., James, C.N., Gidda, S.K., Kilaru, A., Dyer, J.M., Mullen, R.T., Ohlrogge, J.B. and Chapman, K.D. (2013). Identification of a new class of lipid droplet-associated proteins in plants. Plant Physiology, 162(4):1926-36. doi: 10.1104/pp.113.222455.

Horn, P.J., Silva, J.E., Anderson, D., Fuchs, J., Borisjuk, L., Nazarenus, T.J., Shulaev, V., Cahoon, E.B. and Chapman, K.D. (2013). Imaging heterogeneity of membrane and storage lipids in transgenic Camelina sativa seeds with altered fatty acid profiles. Plant Journal, Oct;76(1):138-50. doi: 10.1111/tpj.12278.

Park, S., Gidda, S.K., James, C.N., Horn, P.J., Khuu, N., Seay, D.C., Keereetaweep, J., Chapman, K.D., Mullen, R.T. and Dyer, J.M. (2013). The α/β Hydrolase CGI-58 and peroxisomal transport protein PXA1 co-regulate lipid homeostasis and signaling in Arabidopsis. Plant Cell 25(5):1726-39. (featured in-brief article in same issue)

Horn, P.J., Korte, A.R., Neogi, P.B., Love, E., Fuchs, J., Strupat, K., Borisjuk, L., Shulaev, V., Lee, Y-J. and Chapman, K.D. (2012), Spatial mapping of lipids at cellular resolution in embryos of Gossypium hirsutum, L. Plant Cell, 24:622-636. (featured in-brief article in same issue)

Horn, P.J., Ledbetter, N.R., James, C.N., Hoffman, W.D., Case, C.R., Verbeck, G.F. and Chapman, K.D. (2011). Visualization of lipid droplet composition by direct organelle mass spectrometry. Journal of Biological Chemistry 286(5):3298-306.

James, C.N., Horn, P.J., Case, C.R., Gidda, S.K., Zhang, D., Mullen, R.T., Dyer, J.M., Anderson, R.G. and Chapman, K.D. (2010). Disruption of the Arabidopsis CGI-58 homologue produces Chanarin-Dorfman-like lipid droplet accumulation in plants. Proceedings of the National Academy of Sciences U S A. 107(41):17833-8.

Patents: 
  • Method of enhancing quality factors in cotton; K.D.Hake, K.D. Chapman, T.A. Kerby, T.R. Speed and UNT and Delta and Pine Land Co. US patent number 8,097,768. January 17, 2012.
  • Engineering Lipids in Vegetative tissues of Plants. K.D. Chapman, and.G.W. Anderson. US patent number 8,507,754. August 13, 2013.
  • Methods for Elevating Fat/Oil Content in Plants. V. Puri, K.D. Chapman and J. Christopher N. US patent application number 13830012. March 14, 2013.
  • Method for Enhancing Amidohydrolase Activity of Fatty Acid Amide Hydrolase. J. George, S. Nagarajan, K.D. Chapman, L. Faure, and P. Koulen. US patent application number 20150359218. January 14, 2014.
  • High oleic seed oil trait in cotton varieties to elevate the oleic acid content of cottonseed oil. Chapman, Kent Dean (Denton, TX); Horn, Patrick (Holt, MI); Sturtevant, Drew (Southlake, TX); Kennedy, Christopher (Ft. Worth, TX). US provisional patent application number 62/355,064. June 27, 2016.
  • Methods for increasing oil content in plant tissues by suppressing hydrophobic lipid droplet protein. Chapman, Kent (Denton, TX); Mullen Robert (Guelph, Ontario, Canada); Pyc Michel (Guelph, Ontario, Canada); Dyer, John (Maricopa, AZ). US provisional patent application number 62/350,843. June 16, 2016.