Kent Chapman, PhD. completed a B.A. degree in biology in 1986 from Lycoming College in Williamsport, PA. He then traveled Tempe, AZ, where he earned a Ph.D. degree in botany (plant cell biology) at Arizona State University under the supervision of Richard N. Trelease for studies on peroxisome membrane lipids. After completing his doctoral degree, Chapman was awarded a 2-year NSF postdoctoral fellowship to study plant biochemistry with Thomas S. Moore, Jr., at Louisiana State University in Baton Rouge, LA. In 1993, he accepted a position as a tenure-track, Assistant Professor of Biochemistry at the University of North Texas (UNT) in Denton. During the last 20+ years, Chapman has developed an internationally-recognized research program in plant biochemistry and cell biology, specifically in the area of plant lipid metabolism. The Chapman lab has contributed more than 140 publications to the primary plant biology and biochemistry literature, and new ideas about the evolutionary conservation of lipid metabolism and function in eukaryotes have emerged from these efforts. With John Ohlrogge (Michigan State), Chapman proposed and chaired the inaugural Gordon Research Conference on Plant Lipids: Structure, Metabolism and Function in 2009 in Galveston TX. Chapman is co-inventor on ten patents (issued or pending), and in 2010 was recognized with an award for Outstanding Achievement in Intellectual Property at UNT. Chapman received the first Research Leadership Award at UNT for National and International Scientific Achievement in Research, and in 2017 was re-appointed Regents Professor of Biochemistry. In January, 2014, he took leave from UNT for eighteen months to serve as Program Director at the US National Science Foundation's Division of Integrative Organismal Systems. Chapman currently serves as Director of the BioDiscovery Institute. He is Executive Editor for the journal, Progress in Lipid Research, and reviewing editor for The Plant Cell.
CURRENT RESEARCH INTERESTS:
Lipid signaling in plants.
Compartmentalization of neutral lipids in plant cells.
Plant lipids for human health and industrial applications.
Lipidomics in tissues and organelles.
- United States Department of Energy, Office of Science, Basic Energy Sciences, Physical Biosciences program. Elucidating the Cellular Machinery for Storage Lipids in Plants. (Kent Chapman, PI, Robert Mullen, Co-PI, John Dyer, Co-PI). $1,440,000.00. 9/1/2016 - 8/31/2022 (original and renewal awards).
- Cotton Incorporated; Agreement No 08-395- Annually renewed (since 2008), Genetic Manipulation of Cottonseed Protein Reserves. (Kent Chapman PI). $845,000.00 ($85,000.00 awarded in 2019). 1/1/08-12/31/19 (Current Agreement #16-443; previously #08-895)
- NSF Integrative Organismal Systems (IOS 1656263), Molecular targets and actions of ethanolamide oxylipins in Arabidopsis thaliana. (Kent Chapman PI, Xiaoqiang Wang named senior collaborator). $682,867.00. 3/15/2017-3/14/2020.
- USDA- ARS Cooperative Agreement (sponsor #58-2020-7-019), Engineering Lipid Droplets for Increasing Oil Content and Abiotic Stress Tolerance of Plants. (Kent Chapman PI, John Dyer USDA Cooperator). $71,033.00. 9/1/2017-8/31/2020.
- BASF Plant Science, LP, Embryogenic Cell Culture Screening System for Herbicide Tolerance. (Kent Chapman PI). $242,949.00. 3/1/2018-12/31/2019 (original and two supplement awards)
- United States Department of Energy, Office of Science, Biological and Environmental Research program. Functional Analysis of Candidate Genes Involved in Oil Storage and Stability in Pennycress. (PI Ana Alonso; Kent Chapman and Erich Grotewold, Co-PIs). $ 2,388,159.00. 9/15/2019 - 9/14/2022
MOST SIGNIFICANT PUBLICATIONS
- Romsdahl T, A Shirani, RE Minto, C Zhang, EB Cahoon, KD Chapman*, D Berman* (2019) Nature-Guided Synthesis of Advanced Bio-Lubricants. Nature Scientific Reports 9, Article number: 11711 (2019). *jointly communicated. https://www.nature.com/articles/s41598-019-48165-6
- KD Chapman, M Aziz, JM Dyer, RT Mullen (2019) Mechanisms of lipid droplet biogenesis. Biochemical Journal 476 (13), 1929-1942.
- Cai Y, P Whitehead, J Chappell, KD Chapman (2019) Mouse lipogenic proteins promote the co-accumulation of triacylglycerols and sesquiterpenes in plant cells. Planta, 250 (1): 79-94. Special issue, terpenes.
- Aziz M, X Wang, A Tripathi, VA Bankaitis, KD Chapman (2019) Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. Journal of Biological Chemistry, 294(18): 7419-7432.
- Li X, Teitgen AM, Shirani A, Ling J, Busta L, Cahoon RE, Zhang W, Li Z, Chapman KD, Berman D, Zhang C, Minto RE, Cahoon EB (2018) Discontinuous fatty acid elongation yields hydroxylated seed oil with improved function. Nature Plants 4: 711-720. Altmetric score of 199 places this paper in the 98th percentile of all tracked articles of a similar age in all journals, and ranks it 6th of the 68 tracked articles of a similar age in Nature Plants. See associated News and Views, Nature Plants 4: 633-634.
- Lu S, Sturtevant D, Aziz M Jin C, Li Q, Chapman KD*, Guo L* (2018) Spatial analysis of lipid metabolites and expressed genes reveals tissue‐specific heterogeneity of lipid metabolism in high‐ and low‐oil Brassica napus L. seeds. Plant Journal 94: 915-932 doi: 10.1111/tpj.13959. *joint corresponding authors. Featured Article and Cover. See associated Research highlight- https://doi.org/10.1111/tpj.13966. Plant Journal 94 (6): 913-914.
- Sturtevant D, Aziz M. Chapman KD (2018) Visualizing the oilseed lipidome. Inform 29(4): 21-24. doi: 10.21748/inform.04.2018.21. American Oil Chemist's Society.
- Pyc M, Cai Y, Gidda SK, Yurchenko O, Park S, Kretzschmar FK, Ischebeck T, Valerius O, Braus GH, Chapman KD, Dyer JM, Mullen RT (2017) Arabidopsis lipid droplet-associated protein (LDAP) - interacting protein (LDIP) influences lipid droplet size and neutral lipid homeostasis in both leaves and seeds. Plant Journal 92(6):1182-1201. doi: 10.1111/tpj.13754.
- Keereetaweep, J., Blancaflor, E.B., Hornung, E., Feussner, I. and Chapman, K.D. (2015). Lipoxygenase derived 9-hydro(pero)xides of linoleoylethanolamide interact with ABA signaling to arrest root development during Arabidopsis seedling establishment. Plant Journal 82(2):315-27. doi: 10.1111/tpj.12821.
- Phelps, M.S., Sturtevant, D., Chapman, K.D. and Verbeck, G.F. (2015). Nanomanipulation-coupled matrix-assisted laser desorption/ ionization-direct organelle mass spectrometry: A technique for the detailed analysis of single organelles. Journal of the American Society of Mass Spectrometry (JASMS) 27(2):187-93. PMID: 26238327. (cover of issue)
- Cai, Y., Goodman, J.M., Pyc, M., Mullen, R.T., Dyer, J.M. and Chapman, K.D. (2015). Arabidopsis SEIPIN proteins modulate triacylglycerol accumulation and influence lipid droplet proliferation. Plant Cell 27(9):2616-36. pii: tpc.15.00588.
PATENTS (8 issued, 1 pending):
- US patent #7,199,082, issued April 3, 2007. (WO 01/30143) Methods For Extending The Freshness Of Cut Flowers, Ornamental Trees, And Plant Cuttings, PCT/US00/29959. Kent D. Chapman and Shea Austin-Brown Inventors; University of North Texas is patent holder. Published May 5, 2001, priority date October 28, 1999.
- US patent #7,316,928, issued Jan 8, 2008. (WO 2005/001100) Plant Fatty Acid Amide Hydrolases, PCT/US2004/017690. Kent D. Chapman, Rhidaya Shrestha, Elison Blancaflor, Richard A. Dixon, Published on January 6, 2005, Priority date June 4, 2003. UNT and Noble Foundation are patent holders.
- US Patent #8,097,768, issued January 17, 2012. Method of enhancing quality factors in cotton; Hake; Kater Davis; (Germantown, TN) ; Chapman; Kent Dean; (Denton, TX) ; Kerby; Thomas Arthur; (Scott, MS); Speed; Thomas Rainey; (Wolfforth, TX); Published on February 1, 2007, Priority date June 9, 2006. U.S. Patent Application #11/449,873 UNT and Delta and Pine Land Co. UNT is patent holder.
- US Patent #8,507,754, issued August 13, 2013. Engineering Lipids in Vegetative tissues of Plants. Chapman; Kent Dean (Denton Texas); Anderson, Richard G.W. (Dallas, TX). Filed January 31, 2010 (US Patent Application #12696037). Priority Date January 31, 2009. UNT and UT systems are joint patent holders.
- US Patent #9,474,271, issued October 25, 2016- Method For Enhancing Amidohydrolase Activity of Fatty Acid Amide Hydrolase. John, George (New York, NY); Nagarajan, Subbiah (New York, NY); Chapman, Kent (Denton, TX); Faure, Lionel (Flower Mound, TX); Koulen, Peter (Leawood, KS). Research Foundation of the City University of New York, New York, NY, USA.
- US Patent #9,849,101, issued December 26, 2017. Method For Enhancing Amidohydrolase Activity of Fatty Acid Amide Hydrolase. John, George (New York, NY); Nagarajan, Subbiah (New York, NY); Chapman, Kent (Denton, TX); Faure, Lionel (Flower Mound, TX); Koulen, Peter (Leawood, KS). Research Foundation of the City University of New York, New York, NY, USA.
- US Patent # 10,238,056- HIGH OLEIC SEED OIL TRAIT IN COTTON VARIETIES TO ELEVATE THE OLEIC ACID CONTENT OF COTTONSEED OIL. Chapman, Kent Dean (Denton, TX); Horn, Patrick (Holt, MI); Sturtevant, Drew (Southlake, TX); Kennedy, Christopher (Ft. Worth, TX). Issued March 26, 2019
- US Patent # 10,308,950- METHODS FOR INCREASING OIL CONTENT IN PLANT TISSUES BY SUPPRESSING HYDROPHOBIC LIPID DROPLET PROTEIN. Chapman, Kent (Denton, TX); Mullen Robert (Guelph, Ontario, Canada); Pyc Michel (Guelph, Ontario, Canada); Dyer, John (Maricopa, AZ). Issued June 4, 2019
- US/International Patent Application PCT/US18/65718- LIQUID AND SEMISOLID LUBRICANT COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF Inventor(s): Diana Berman, Kent Dean Chapman, Trevor Bradley Romsdahl, Edgar Benjamin Cahoon, Robert Earl Minto, December 14, 2018. Pending.